Application
Western blot analysis of PTP-MEG2 expression in A549 whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung carcinoma tissue showing cytoplasmic localization.| Product Name | PTP-MEG2 Antibody (U-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of PTP-MEG2 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | Protein tyrosine phosphatases (PTPs) and protein tyrosine kinases (PTKs) play a ubiquitous role in the regulation of tyrosine phosphorylation-mediated signaling pathways. Tyrosine-phosphorylated proteins can be dephosphorylated through the action of PTPs, which therefore are likely to play a regulatory role in the control of cellular growth and differentiation. PTP-MEG2 (also known as PTPN9) is a cytoplasmic nonreceptor protein involved in the transfer of hydrophobic ligands and possibly in functions of the Golgi apparatus. It is involved in the development of erythroid cells and has an N-terminal Sec14p homology domain. The human gene for PTP-PEST, another cytoplasmic nonreceptor protein, maps to chromosome 7q11.23 and encodes a 780 amino acid cytosolic nonreceptor protein. PTP-PEST is expressed abundantly in a wide variety of hemopoietic cell types, including B cells and T cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of PTP-MEG2 of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of PTP-MEG2 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 5780 |
|---|
Application
Western blot analysis of PTP-MEG2 expression in A549 whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung carcinoma tissue showing cytoplasmic localization.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
