| Product Name | RFRP-1 Antibody (H-37) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 56-92 mapping within an internal region of RFamide-related peptides precursor protein of human origin |
| Modification Notes | The human RFamide-related peptide gene, RFRP (also designated NPVF or C7orf9), is responsible for encoding three small neuropeptides designated RFRP-1 (NPSF), RFRP-2 and RFRP-3 (NPVF). The homologous gene in rodents encodes only two functional neuropeptide: RFRP-1 (NPSF) and RFRP-3 (NPVF). RFamide-related peptides constitute a large family of neuropeptides in a wide range of species that are known to play a role in neurotransmission, neuromodulation, cardioexcitation and control of muscle contraction. Neuropeptides RFRP-1 and RFRP-3 efficiently inhibit Forskolin-induced production of cAMP. RFRP-2, however, does not appear to have a similar inhibitory activity. RFamide-related peptides are secreted and abundantly expressed in retina. RFRP-1 and RFRP-3 are also widely distributed in fetal and adult brain, including the forebrain, hypothalamus, thalamus, midbrain, pons and medulla oblongata. RFRP-1 and the prolactin (PRL)-releasing peptide-31 (PrRP-31) may be involved in the stimulation of stress hormone secretion by either direct pituitary or indirect hypothalamic actions. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RFamide-related peptides precursor protein and RFRP-1 active peptide of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 56-92 mapping within an internal region of RFamide-related peptides precursor protein of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 56-92 mapping within an internal region of RFamide-related peptides precursor protein of human origin |
| Entrez Gene | 64111 |
|---|
| Application Notes | recommended for detection of RFamide-related peptides precursor protein and RFRP-1 active peptide of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
