| Product Name | PMS7 Antibody (N-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of PMS7 of human origin |
| Modification Notes | PMS7 (postmeiotic segregation increased protein 7), also known as PMS2P5 (postmeiotic segregation increased 2 pseudogene 5), PMS2L5 (postmeiotic segregation increased 2-like protein 5) or PMS4 (postmeiotic segregation increased protein 4), is a 134 amino acid protein that belongs to the DNA mismatch repair mutL/hexB family. Participating in ATP binding and in mismatched DNA binding, PMS7 is likely a predominant target for regulation by p53. PMS7 is reactive to DNA damage and p53 activation in normal human fibroblasts, and contains p53-response elements within its first intron. PMS7 may function as a sensor in DNA repair mechanisms and may act as a critical determinant for the decision between cell-cycle arrest and apoptosis. The gene that encodes PMS7 maps to human chromosome 7q11.23. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PMS7 and LOC100132832 of human origin by WB, IF and ELISA non cross-reactive with other PMS family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of PMS7 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of PMS7 of human origin |
| Entrez Gene | 5383 |
|---|
| Application Notes | recommended for detection of PMS7 and LOC100132832 of human origin by WB, IF and ELISA non cross-reactive with other PMS family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
