Application
Western blot analysis of NMD3 expression in mouse heart tissue extract (A) and T-47D whole cell lysate (B).| Product Name | NMD3 Antibody (L-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of NMD3 of mouse and human origin by WB, IP and ELISA |
| Modification Notes | Ribosomal subunits are synthesized in the nucleus and mature 40S and 60S subunits are exported stoichiometrically into the cytoplasm. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. Ribosomal proteins have the ability to pass through the nuclear envelope in the native state, making them the largest of the structures accommodated by the nuclear pore complexes. Nuclear export of the 60S ribosomal subunit depends on the adapter protein NMD3, which contains a CRM-1-dependent leucine-rich nuclear export signal (NES) and a complex, dispersed nuclear localization signal (NLS). The gene encoding NMD3 is located on human chromosome 3, which encodes over 1,100 genes and contains a variety of human cancer related loci. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of NMD3 of mouse and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of NMD3 of mouse and human origin by WB, IP and ELISA |
| Entrez Gene | 51068 |
|---|
Application
Western blot analysis of NMD3 expression in mouse heart tissue extract (A) and T-47D whole cell lysate (B).| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
