| Product Name | VpreB Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 91-145 mapping at the C-terminus of VpreB of human origin |
| Modification Notes | VpreB (also known as CD179a or pre-B lymphocyte 1) is expressed in pre-B lymphocytes, but not in mature B cells or in other blood cell lineages. The gene which encodes VpreB maps to human chromosome 22q11.2. The VpreB and lambda 5 genes encode the iota and omega polypeptide chains, respectively, which associate with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B cells. This complex presumably regulates Ig gene rearrangements in the early steps of B cell differentiation. In the mouse the two genes are simultaneously expressed in pre-B cells and belong to the same transcription unit. A primary transcript is synthesized from which the pre-B and lambda 5 mRNAs are derived by alternative splicing. In the human, however, the two genes are separate and do not belong to the same transcription unit. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of VpreB of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 91-145 mapping at the C-terminus of VpreB of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 91-145 mapping at the C-terminus of VpreB of human origin |
| Entrez Gene | 7441 |
|---|
| Application Notes | recommended for detection of VpreB of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
