| Product Name | MFT Antibody (P-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of MFT of human origin |
| Modification Notes | Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydofolate into the cell. MFT (Mitochondrial folate transporter/carrier), also known as Solute carrier family 25 member 32 (SLC25A32), is a 315 amino acid multi-pass membrane protein that regulates the influx of folate into the mitochondria. MFT also functions to complement glycine auxotrophy. Mutations in the gene encoding MFT may be involoved in certain cases of multiple acyl-CoA dehydrogenase deficiency (MADD), in which there is no mutation in EFTA or EFTB genes. MADD is a autosomal recessively inherited disorder in which fatty acid, amino acid and choline metabolism is disrupted, leading to a clinical manisfestation of hypoglycemia, hypotonia, hepatomegaly, metabolic acidosis and dysplastic kidneys. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of MFT of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of MFT of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of MFT of human origin |
| Entrez Gene | 81034 |
|---|
| Application Notes | recommended for detection of MFT of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
