Application
Western blot analysis of TIP39 expression in Hep G2 whole cell lysate.| Product Name | TIP39 Antibody (Z-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of TIP39 of mouse, rat and human origin by WB, IP and ELISA |
| Modification Notes | Tuberoinfundibular peptide of 39 residues (TIP39) and the parathyroid hormone-2 (PTH2) receptor form part of an extended family of related signaling molecules that includes the PTH1 receptor, which responds to PTH and PTH-related protein. The polypeptide TIP39 is a potent activator of the parathyroid hormone (PTH)-2 receptor (PTH2, P2R) and an antagonist of the PTH-1 receptor (PTH1, P1R). TIP39 stimulates cAMP accumulation in cells expressing PTH2, but it is inactive at the PTH1 receptor site. The TIP39 gene encoding the protein maps at chromosome 19q13.33. TIP39 may have an important role in spermatogenesis. Mouse TIP39 differs from human TIP39 by four amino acid residues. TIP39 expression can be seen in testis, seminiferous tubuli, liver, kidney and in several brain regions such as nucleus subparafascicularis thalami, nucleus centralis pontis and nucleus ruber. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TIP39 of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of TIP39 of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 113091 |
|---|
Application
Western blot analysis of TIP39 expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
