| Product Name | SLM-1 Antibody (H-130) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 220-349 mapping at the C-terminus of SLM-1 of human origin |
| Modification Notes | Sam 68 is phosphorylated on tyrosine and functions as a substrate for src family tyrosine kinases during mitosis. Sam 68 also associates with several SH2 and SH3 domain-containing signaling proteins, such as GRB2 and PLC g1. Originally cloned as Ras GAP-associated p62, further investigations have shown that Sam 68 and Ras GAP-associated p62 are not antigenically related, nor are they encoded by the same gene. Like Sam 68, the Sam 68-like mammalian proteins, SLM-1 and SLM-2, demonstrate RNA binding activity. Also like Sam 68, SLM-1 is tyrosine phosphorylated and functions as an adapter protein for signaling molecules, including GRB2, PLC g1, Fyn and RasGAP. SLM-2 is not tyrosine phosphorylated, nor does it appear to associate with GRB2, PLC g1, Fyn or RasGAP, indicating that SLM-2 may not be an adapter protein for these proteins. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SLM-1 and, to a lesser extent, SLM-2 and Sam 68 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 220-349 mapping at the C-terminus of SLM-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 220-349 mapping at the C-terminus of SLM-1 of human origin |
| Entrez Gene | 202559 |
|---|
| Application Notes | recommended for detection of SLM-1 and, to a lesser extent, SLM-2 and Sam 68 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
