Application
Western blot analysis of TRIM16 expression in Hep G2 whole cell lysate.| Product Name | TRIM16 Antibody (G-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of TRIM16 of human origin by WB, IP and ELISA |
| Modification Notes | The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM16 (tripartite motif-containing 16), also known as EBBP (Estrogen-responsive B box protein), is a 564 amino acid protein that belongs to the TRIM family and contains two B box-type zinc fingers and one B30.2/SPRY domain. TRIM16 is highly expressed in testis, ovary, small intestine, colon, placenta, heart, skeletal muscle and mammary gland. However, it is more highly expressed in fetus than in the corresponding adult tissues. TRIM16 is also expressed in basal keratinocytes, where it is thought to play a role in the regulation of keratinocyte differentiation. Overexpression of TRIM16 has been shown to increase histone acetylation in retinoid-resistant cancer cells and therefore may be a potential target for therapeutic drugs. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TRIM16 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of TRIM16 of human origin by WB, IP and ELISA |
| Entrez Gene | 10626 |
|---|
Application
Western blot analysis of TRIM16 expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
