Application
Western blot analysis of RBM14 expression in SP2/0 whole cell lysate.| Product Name | RBM14 Antibody (Q-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of RBM14 of mouse and rat origin by WB, IP and ELISA |
| Modification Notes | RBM14 (RNA-binding protein 14), also known as SIP, CoAA, PSP2, SYTIP1 or TMEM137, is a 669 amino acid protein that localizes to the nucleus and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously with higher expression in heart, brain, liver, kidney, colon, lung and skeletal muscle, RBM14 exists as two alternatively spliced isoforms which exhibit different cellular functions. Isoform one, designated CoAA, is thought to function as a nuclear receptor coactivator which interacts with MSG1 and PRIP and, via these interactions, may enhance transcription. Alternatively, isoform two, known as CoAM, is thought to function as a transcriptional repressor which may modulate the transcriptional activities of coactivators, including CoAA. Via its ability to control transcription, RBM14 may be involved in the pathogenesis of several cancers, such as kidney cell carcinoma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of RBM14 of mouse and rat origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of RBM14 of mouse and rat origin by WB, IP and ELISA |
| Entrez Gene | 56275 |
|---|
Application
Western blot analysis of RBM14 expression in SP2/0 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
