| Product Name | ABHD5 Antibody (H-48) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 179-226 mapping within an internal region of ABHD5 of human origin |
| Modification Notes | Alpha/beta-hydrolase domains are characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. ABHD5 (abhydrolase domain containing 5), also known as CGI-58, NCIE2 or CDS, is a 349 amino acid protein that contains an alpha/beta-hydrolase domain through which it conveys catalytic function. Localized to the surface of lipid droplets, ABHD5 is widely expressed and interacts with Perilipin on the surface of lipid droplets where it facilitates lipolysis, the breakdown of fat. Defects in the gene encoding ABHD5 are the cause of Chanarin-Dorfman syndrome (CDS), an autosomal recessive inborn error of lipid metabolism with impaired long-chain fatty acid oxidation. CDS symptoms include congenital generalized ichthyosis, vacuolated leukocytes, hepatomegaly, myopathy, cataracts, neurosensory hearing loss and developmental delay. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ABHD5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 179-226 mapping within an internal region of ABHD5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 179-226 mapping within an internal region of ABHD5 of human origin |
| Entrez Gene | 51099 |
|---|
| Application Notes | recommended for detection of ABHD5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
