Application
Western blot analysis of TEX2 expression in Jurkat whole cell lysate.| Product Name | TEX2 Antibody (X-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of TEX2 of mouse and human origin by WB, IP and ELISA |
| Modification Notes | TEX2 (Testis-expressed sequence 2 protein) is a 1,127 amino acid multi-pass membrane protein that is specifically expressed in testis. There are two isoforms of TEX2 that are produced as a result of alternative splicing events. The gene encoding TEX2 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Chromosome 17 has also been implicated in the pathogenesis of frontaotemporal dementia and parkinsonism. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TEX2 of mouse and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of TEX2 of mouse and human origin by WB, IP and ELISA |
| Entrez Gene | 55852 |
|---|
Application
Western blot analysis of TEX2 expression in Jurkat whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
