| Product Name | Cup1 Antibody (y-61) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-61 representing full length Cup1 of Saccharomyces cerevisiae origin |
| Modification Notes | The activity of a diverse subset of enzymes relies on the essential nutrient copper. Copper uptake requires tight regulation to ensure that sufficient copper is present in the cell to drive vital cellular processes, while avoiding the accumulation of copper to toxic levels. In Saccharomyces cerevisiae, copper regulation involves several proteins. Fre1, a surface reductase, reduces and mobilizes copper outside the cell, while the Ctr1 and Ctr3 proteins function as copper transport proteins within the plasma membrane. Regulation of these proteins occurs at the transcriptional level. Cup1, a metallothionein-like protein, binds copper and protects S. cerevisiae from copper poisoning. Ace1 activates CUP1 transcription in response to copper ions. Heat shock transcription factor also activates CUP1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Cup1 of Saccaromyces cerevisiae origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-61 representing full length Cup1 of Saccharomyces cerevisiae origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-61 representing full length Cup1 of Saccharomyces cerevisiae origin |
| Application Notes | recommended for detection of Cup1 of Saccaromyces cerevisiae origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
