Application
Western blot analysis of ARH2 expression in non-transfected: (A) and mouse ARH2 transfected: (B) 293T whole cell lysates.| Product Name | ARH2 Antibody (K-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ARH2 of human origin |
| Modification Notes | ARH2 (ADP-ribosylhydrolase 2), also known as ADPRHL1 (ADP-ribosylhydrolase like 1), is a 354 amino acid protein that catalyzes the removal of ADP-ribose from target proteins. ARH2 is expressed as two alternatively spliced isoforms which are encoded by a gene that maps to human chromosome 13. Comprising nearly 4% of the human genome, chromosome 13 contains around 114 million base pairs and encodes over 400 genes. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ARH2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ARH2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ARH2 of human origin |
| Entrez Gene | 113622 |
|---|
Application
Western blot analysis of ARH2 expression in non-transfected: (A) and mouse ARH2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of ARH2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
