Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung carcinoma tissue showing cytoplasmic staining.| Product Name | PLAA Antibody (C-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of PLAA of human origin by IF, IHC(P) and ELISA |
| Modification Notes | WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. PLAA, also known as PLAP (Phospholipase A-2-activating protein) or DOA1, is a 795 amino acid protein that contains one PFU domain, one PUL domain and seven WD repeats. Via its regulatory domains, PLAA interacts with and activates phospholipase A2 (PLA2), thereby playing an important role in the regulation of inflammatory disease processes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFIHCELISA |
| IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of PLAA of human origin by IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of PLAA of human origin by IF, IHC(P) and ELISA |
| Entrez Gene | 9373 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung carcinoma tissue showing cytoplasmic staining.| Application Notes | IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
