Application
Western blot analysis of PRODH2 expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human intestine tissue showing cytoplasmic staining.| Product Name | PRODH2 Antibody (S-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against PRODH2 of human origin |
| Conjugation | Agarose |
| Modification | Acetylated |
| Modification Notes | Probable proline dehydrogenase 2 (PRODH2), also known as HSPOX1 or kidney and liver proline oxidase 1, is a 536 amino acid member of the proline oxidase family. The primary function of PRODH2 is to convert proline into delta-1-pyrroline-5-carboxylate (P5C). Proline, functioning as a source of glutamate, arginine and tricarboxylic acid cycle intermediates and taking part in shuttling redox equivalents between mitochondria and cytosol, plays a critical role in protein synthesis. P5C, with the help of ALDH4A1 (also known as 1-pyrroline-5-carboxylate dehydrogenase or P5CDH), is converted into glutamate, one of the most common neurotransmitters in the brain. The PRODH2 gene maps to chromosome 19q13.12, and mutations in this gene have been associated with increased susceptibility to schizophrenia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHCIPWB |
| WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 IHC:1:10~1:50 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against PRODH2 of human origin |
|---|---|
| Tissue Specificity | raised against PRODH2 of human origin |
| Entrez Gene | 58510 |
|---|
Application
Western blot analysis of PRODH2 expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human intestine tissue showing cytoplasmic staining.| Application Notes | WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 IHC:1:10~1:50 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
