Application
Western blot analysis of LARP1 expression in Hep G2 whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining.| Product Name | LARP1 Antibody (P-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against LARP1 of human origin |
| Modification Notes | La-related protein 1 (LARP1), also known as KIAA0731, is a 1,096 amino acid protein belonging to the LARP family. LARP1 contains two conserved regions, one that shares homology with La/SSB proteins and one that is conserved only across LARP family proteins. Within the La/SSB conserved region, LARP1 contains a HTH La-type RNA-binding domain, which may indicate a role in RNA stabalization and folding. Upon DNA damage, LARP1 is phosphorylated by ATR or ATM. LARP1 interacts with many signaling intermediate proteins, including 14-3-3 ∫ , 14-3-3 © , 14-3-3 † and 14-3-3 Ω. Widely expressed, LARP1 levels are highest in heart. LARP1 exists as three isoforms produced by alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of LARP1 of human, rat and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against LARP1 of human origin |
|---|---|
| Tissue Specificity | raised against LARP1 of human origin |
| Entrez Gene | 23367 |
|---|
Application
Western blot analysis of LARP1 expression in Hep G2 whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining.| Application Notes | recommended for detection of LARP1 of human, rat and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
