Application
Western blot analysis of HNRPLL expression in 293T whole cell lysate.Application
Western blot analysis of HNRPLL expression in Hep G2 whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart tissue showing nuclear staining.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing nuclear staining.| Product Name | HNRPLL Antibody (P-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against HNRPLL of human origin |
| Modification Notes | Heterogeneous nuclear ribonucleoprotein L-like (HNRPLL), also known as stromal RNA-regulating factor (SRRF), is a 542 amino acid nuclear protein. HNRPLL shares 69% amino acid homology with hnRNP L, a protein that binds to the 3’ end of introns to modulate alternative splicing mechanisms of pre-mRNAs in normal cells. Due to this homology, HNRPLL is thought to bind RNA and participate in mRNA processing. HNRPLL contains three RNA-regulating motif (RRF) domains, which have RNA-binding regions. HNRPLL interacts with BAT1, an RNA-dependent ATPase that controls ATP hydrolysis during pre-mRNA splicing. HNRPLL is widely expressed in human tissues, including pancreas, lung, kidney, placenta, heart, skeletal muscle and bone marrow stromal cells. HNRPLL is expressed as four isoforms produced by alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of HNRPLL of human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against HNRPLL of human origin |
|---|---|
| Tissue Specificity | raised against HNRPLL of human origin |
| Entrez Gene | 92906 |
|---|
Application
Western blot analysis of HNRPLL expression in 293T whole cell lysate.
Application
Western blot analysis of HNRPLL expression in Hep G2 whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart tissue showing nuclear staining.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing nuclear staining.| Application Notes | recommended for detection of HNRPLL of human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
