GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. TBC1D10B (TBC1 domain family member 10B), also known as FP2461, is a 533 amino acid protein that contains one Rab-GAP TBC domain, a highly conserved 200 amino acid motif that conveys the the catalytic activity of GTPase-activating proteins. Via its Rab-GAP domain, TBC1D10B is thought to function as a GTPase-activating protein that may regulate the activity of target Rab proteins. TBC1D10B exists as two alternatively spliced isoforms which are encoded by a gene that is located on chromosome 16.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of TBC1D10B of human origin by WB, IP and ELISA: