Application
Western blot analysis of G6f expression in K-562 (A) and A-431 (B) nuclear extracts and Jurkat whole cell lysate (C).Application
Western blot analysis of G6f expression in A-431 nuclear extract.Application
Western blot analysis of G6f expression in Hep G2 whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining.| Product Name | G6f Antibody (Q-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against G6f of human origin |
| Modification Notes | G6f, also known as lymphocyte antigen 6 complex locus protein G6f, is a single-pass type I membrane protein belonging to the immunoglobulin (Ig) superfamily. Located in the class III region of the major histocompatibility complex (MHC), the G6f gene lies in a cluster of genes encoding cell-surface proteins that play a role in the immune system and cellular recognition. G6f functions as a downstream effector of GRB2 and GRB7, and, in humans, it interacts with GRB2 and GRB7 through the phosphorylation of a tyrosine residue (Tyr 281) in the intracellular tail of G6f. This interaction is also mediated by the SH2 domain of GRB2 and possibly that of GRB7. G6f is a 297 amino acid protein, and it forms a disulfide-linked homodimer. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of G6f of human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against G6f of human origin |
|---|---|
| Tissue Specificity | raised against G6f of human origin |
| Entrez Gene | 259215 |
|---|
Application
Western blot analysis of G6f expression in K-562 (A) and A-431 (B) nuclear extracts and Jurkat whole cell lysate (C).
Application
Western blot analysis of G6f expression in A-431 nuclear extract.
Application
Western blot analysis of G6f expression in Hep G2 whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining.| Application Notes | recommended for detection of G6f of human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
