Application
Western blot analysis of AIP5 expression in A-431 whole cell lysate.| Product Name | AIP5 Antibody (H-260) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 91-350 mapping within an internal region of AIP5 of human origin |
| Modification Notes | Atrophin interacting proteins (AIP)s bind to atrophin-1 in the vicinity of the polyglutamine tract (1,2). The WW domain consists of 35-40 amino acids and is characterized by four well conserved aromatic residues, two of which are tryptophan (3-6). All five AIPs contain multiple WW domains and can be divided into two distinct classes (1). AIP1 and AIP3 (WWP3) are MAGUK-like multidomain proteins containing a guanylate kinase-like region, two WW domains, and multiple PDZ domains (1). AIP2 (WWP2), AIP4 (itchy), and AIP5 (WWP1) are highly homologous, each having four WW domains and a HECT domain characteristic of ubiquitin ligases (1-3). These interactors are similar to isolated huntingtin-interacting proteins, suggesting commonality of function between two families of proteins responsible for similar diseases (1-3). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of AIP5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 91-350 mapping within an internal region of AIP5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 91-350 mapping within an internal region of AIP5 of human origin |
| Entrez Gene | 11059 |
|---|
Application
Western blot analysis of AIP5 expression in A-431 whole cell lysate.| Application Notes | recommended for detection of AIP5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
