epitope corresponding to amino acids 1-300 mapping at the N-terminus of PTP-MEG2 of human origin
Modification Notes
Protein tyrosine phosphatases (PTPs) and protein tyrosine kinases (PTKs) play a ubiquitous role in the regulation of tyrosine phosphorylation-mediated signaling pathways. Tyrosine-phosphorylated proteins can be dephosphorylated through the action of PTPs, which therefore are likely to play a regulatory role in the control of cellular growth and differentiation. PTP-MEG2 (also known as PTPN9) is a cytoplasmic nonreceptor protein involved in the transfer of hydrophobic ligands and possibly in functions of the Golgi apparatus. It is involved in the development of erythroid cells and has an N-terminal Sec14p homology domain. The human gene for PTP-PEST, another cytoplasmic nonreceptor protein, maps to chromosome 7q11.23 and encodes a 780 amino acid cytosolic nonreceptor protein. PTP-PEST is expressed abundantly in a wide variety of hemopoietic cell types, including B cells and T cells.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of PTP-MEG2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-300 mapping at the N-terminus of PTP-MEG2 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-300 mapping at the N-terminus of PTP-MEG2 of human origin
Western blot analysis of PTP-MEG2 expression in non-transfected: (A) and human PTP-MEG2 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of PTP-MEG2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.