Application
Western blot analysis of CXCR-3 expression in HeLa whole cell lysate.| Product Name | CXCR-3 Antibody (H-95) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-95 mapping at the N-terminus of CXCR-3 of human origin |
| Modification Notes | The C-X-C or å chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). SDF-1 was originally described as a pre-B cell stimulatory factor, but has since been shown to function as a potent chemoattractant for T cells and monocytes but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB, CXCR-3 and fusin (also designated LESTR or CXCR-4). CXCR-3, also known as IP-10/MIG receptor, mediates Ca2+ mobilization and chemotaxis in response to the C-X-C chemokines IP-10 and MIG. CXCR-3 is highly expressed in IL-2-activated T lymphocytes, but not in resting T lymphocytes, B lymphocytes, monocytes or granulocytes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CXCR-3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-95 mapping at the N-terminus of CXCR-3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-95 mapping at the N-terminus of CXCR-3 of human origin |
| Entrez Gene | 2833 |
|---|
Application
Western blot analysis of CXCR-3 expression in HeLa whole cell lysate.| Application Notes | recommended for detection of CXCR-3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
