epitope corresponding to amino acids 681-730 mapping within a C-terminal cytoplasmic domain of OB-cadherin of human origin
Modification Notes
The cadherins are a family of Ca++-dependent adhesion molecules that influence cell-cell binding and are critical to the maintenance of tissue structure and morphogenesis. OB-cadherin (osteoblast-cadherin, cadherin-11, OSF-4) has two forms, OB-cadherin-1 and OB-cadherin-2. OB-cadherin-2 has a truncated cytoplasmic domain, missing amino acids 694-796. Both OB-cadherins are expressed in osteoblastic cell lines with low expression seen in lungs, testis and brain.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of OB-cadherin (cadherin-11) and, to a lesser extent cadherin-8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 681-730 mapping within a C-terminal cytoplasmic domain of OB-cadherin of human origin
Tissue Specificity
epitope corresponding to amino acids 681-730 mapping within a C-terminal cytoplasmic domain of OB-cadherin of human origin
Western blot analysis of OB-cadherin expression in rat brain tissue extract.
Application Notes
recommended for detection of OB-cadherin (cadherin-11) and, to a lesser extent cadherin-8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.