| Product Name | DP Antibody (H-48) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 217-264 mapping within an extracellular domain of DP of human origin |
| Modification Notes | DP (prostanoid DP receptor or prostaglandin D2 receptor), also known as AS1 or ASRT1, is a member of the G-protein coupled receptor 1 family. It localizes to the cell membrane and is widely expressed, found in cells and tissues such as lung, platelets, nasal mucosa, small intestine and retina. DP functions as one of the two receptors for prostaglandin D2 (the other being CRTH2). Responses mediated by DP include mucin secretion, vasorelaxation via synthesis of intracellular cAMP, inhibition of platelet aggregation, and the lowering of intraocular pressure. DP also plays an important role in eosinophil trafficking and may serve as a target protein in the treatment of allergic disease. Variations in the gene encoding DP are implicated in the susceptibility to asthma-related traits including symptoms such as wheezing, coughing and dyspnea. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Prostanoid DP receptor of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 217-264 mapping within an extracellular domain of DP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 217-264 mapping within an extracellular domain of DP of human origin |
| Entrez Gene | 5729 |
|---|
| Application Notes | recommended for detection of Prostanoid DP receptor of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
