epitope corresponding to amino acids 211-275 mapping within an internal region of LOXL4 of mouse origin
Modification Notes
Lysyl oxidase (LOX) proteins belong to a family of enzymes that oxidize primary amine substrated to reactive aldehydes. In fibrillar collagens and elastin, LOX catalyzes the lysine-derived cross-links of collagen fibrils and insoluble elastic fibers within the extracellular matrix. It can localize both to the nucleus and the cytoplasm. LOX is involved in tumor suppression, cell motility, cellular senescence and developmental regulation. There are four homologs of LOX, lysyl oxidase-like proteins designated LOX-like (LOXL1-LOXL4) proteins. LOXL4 is an extracellular protein that is widely expressed. Highest expression levels have been detected in testis, pancreas, cartilage and skeletal muscle.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of LOXL4 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 211-275 mapping within an internal region of LOXL4 of mouse origin
Tissue Specificity
epitope corresponding to amino acids 211-275 mapping within an internal region of LOXL4 of mouse origin