Application
Western blot analysis of Fibromodulin expression in non-transfected: (A) and human Fibromodulin transfected: (B) 293T whole cell lysates.| Product Name | Fibromodulin Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 301-350 mapping near the C-terminus of Fibromodulin of human origin |
| Modification Notes | Small leucine-rich proteoglycans (SLRPs) such as Decorin, Biglycan, Fibromodulin, and Lumican mediate extracellular matrix organization and are binding partners of TGFbeta. Fibromodulin is a collagen-binding Keratan sulphate proteoglycan that influences adhesion processes of connective tissue, and plays a role in fibrillogenesis by regulating collagen fibril spacing and thickness. The core proteins of SLRPs consist of a central region of leucine-rich repeats flanked by disulfide-linkages of the terminal domains. Fibromodulin is a ubiquitous protein that is most prominent in articular cartilage, tendon, and ligament. The human Fibromodulin gene maps to chromosome 1q32 and encodes a 376 amino acid protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Fibromodulin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 301-350 mapping near the C-terminus of Fibromodulin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 301-350 mapping near the C-terminus of Fibromodulin of human origin |
| Entrez Gene | 2331 |
|---|
Application
Western blot analysis of Fibromodulin expression in non-transfected: (A) and human Fibromodulin transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Fibromodulin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
