Application
Western blot analysis of NP2 expression in non-transfected: (A) and human NP2 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of NP2 expression in non-transfected: (A) and human NP2 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of NP2 expression in non-transfected: (A) and human NP2 transfected: (B) 293T whole cell lysates.| Product Name | NP2 Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 382-431 mapping at the C-terminus of NP2 of human origin |
| Modification Notes | Long pentraxins are a family of highly conserved proteins that are expressed in the brain and central nervous system, and form multimeric complexes (1-4). Neuronal pentraxin 1 (NP1), NP2, and neuronal pentraxin receptor (NPR) are members of the long pentraxins that represent a neuronal uptake pathway that may function during synapse formation and remodeling (5). The NP1 gene is located on chromosome 17q25.3 and the protein product mediates the uptake of synaptic material, including the presynaptic snake venom toxin, taipoxin (3). NP2, whose function is unknown, is located on chromosome 7q22.1 and like NP1 contains several potential N-linked glycosylation sites (3,4). NPR is expressed on the cell membrane and can form heteropentamers with NP1 and NP2 that can be released from the cell membrane by proteolysis (5). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NP2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 382-431 mapping at the C-terminus of NP2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 382-431 mapping at the C-terminus of NP2 of human origin |
| Entrez Gene | 4885 |
|---|
Application
Western blot analysis of NP2 expression in non-transfected: (A) and human NP2 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of NP2 expression in non-transfected: (A) and human NP2 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of NP2 expression in non-transfected: (A) and human NP2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of NP2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
