Application
Western blot analysis of Serglycin expression in non-transfected: (A) and human Serglycin transfected: (B) 293 whole cell lysates.| Product Name | Serglycin Antibody (FL-158) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-158 representing full length Serglycin of human origin |
| Modification Notes | Proteoglycans stored in the secretory granules of many hematopoietic cells contain a protease-resistant peptide core that may be important for neutralizing hydrolytic enzymes. Serglycin is associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Serglycin is a chondroitin sulfate-bearing proteoglycan that functions in the transport of cationic granular proteins. The immune system relies on granule exocytosis as the main pathway for elimination of virus-infected cells and tumor cells by cytotoxic T lymphocytes and natural killer cells, thus indicating an important role for serglycin in normal immune function. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of precursor and mature Serglycin of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-158 representing full length Serglycin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-158 representing full length Serglycin of human origin |
| Entrez Gene | 5552 |
|---|
Application
Western blot analysis of Serglycin expression in non-transfected: (A) and human Serglycin transfected: (B) 293 whole cell lysates.| Application Notes | recommended for detection of precursor and mature Serglycin of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
