| Product Name | RIP5 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 630-929 mapping at the C-terminus of RIP5 of human origin |
| Modification Notes | The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. RIP5 (receptor interacting protein kinase 5), also known as RIPK5, DustyPK or SGK496 (Sugen kinase 496), is a 929 amino acid protein that localizes to the cytoplasm, contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed at low levels in placenta, heart, brain, kidney, pancreas, testis and skeletal muscle, RIP5 catalyzes the ATP-dependent phosphorylation of target proteins and is thought to induce both caspase-dependent and -independent cell death. Four isoforms of RIP5 exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RIP5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 630-929 mapping at the C-terminus of RIP5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 630-929 mapping at the C-terminus of RIP5 of human origin |
| Entrez Gene | 25778 |
|---|
| Application Notes | recommended for detection of RIP5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
