The Golgi complex plays an essential role in the post-translational modification and sorting of proteins transported from the endoplasmic reticulum (ER). The Golgi stack consists of a distinct cis face, or entry face, and a trans face, or exit face, which are connected via the cis, medial and trans Golgi networks. GOLT1B (golgi transport 1B), also known as putative NF-kappa-B-activating protein 470 or hGOT1a, is a 138 amino acid multi-pass membrane protein that belongs to the GOT1 family. Localizing to Golgi apparatus, GOLT1B may play a role in the fusion of ER-derived transport vesicles to the Golgi complex. The gene encoding GOLT1B maps to human chromosome 12p12.1 and mouse chromosome 6 G2. Human chromosome 12 encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of GOLT1B of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with GOLT1A also reactive with additional species, including equine, canine, bovine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within a C-terminal cytoplasmic domain of GOLT1B of human origin
Tissue Specificity
epitope mapping within a C-terminal cytoplasmic domain of GOLT1B of human origin
Western blot analysis of GOLT1B expression in non-transfected: (A) and human GOLT1B transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of GOLT1B of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with GOLT1A also reactive with additional species, including equine, canine, bovine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.