| Product Name | EI24 Antibody (H-101) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 181-281 mapping within an internal region of EI24 of human origin |
| Modification Notes | EI24 (etoposide-induced protein 2.4 homolog), also known as PIG8 (p53-induced gene 8 protein), is a 340 amino acid multi-pass membrane protein that belongs to the El24 family and interacts with Bcl-2. Acting as a negative growth regulator via the p53-mediated apoptosis pathway, EI24 regulates the formation of degradative autolysosomes during autophagy. The gene encoding El24 consists of approximately 15,464 bases and maps to human chromosome 11q24.2. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of EI24 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 181-281 mapping within an internal region of EI24 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 181-281 mapping within an internal region of EI24 of human origin |
| Entrez Gene | 9538 |
|---|
| Application Notes | recommended for detection of EI24 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
