| Product Name | St3Gal-II Antibody (H-150) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-150 mapping at the N-terminus of St3Gal-II of human origin |
| Modification Notes | Cell type-specific expression of unique carbohydrate structures on cell surface glycoproteins and glycolipids provides information relevant to cell-cell interactions in developing and adult organisms. Sialyltransferases contribute to the diversity of carbohydrate structures through their attachment of sialic acid to various terminal positions on glycolipid and glycoprotein (N-linked and O-linked) carbohydrate groups. St3Gal-II (St3 beta-galactoside alpha-2,3-sialyltransferase 2), also known as SIAT4B, Gal-NAc6S, ST3GAL2 or ST3GalA.2, is a member of the glycosyltransferase 29 family of proteins. Predominantly expressed in heart and skeletal muscle, St3Gal-II exists as a single-pass membrane protein localizing to the Golgi apparatus. In addition to forward sialylation reactions (the transfer of NeuAc from CMP-NeuAc to galactose-containing substrates), St3Gal-II readily catalyzes reversible sialylation reactions (the transfer of NeuAc from sialylated donors to CMP (cytidine 5’-monophosphate)). This reverse reaction provides newly synthesized CMP-NeuAc which is then available for transfer to another acceptor. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of St3Gal-II of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-150 mapping at the N-terminus of St3Gal-II of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-150 mapping at the N-terminus of St3Gal-II of human origin |
| Entrez Gene | 6483 |
|---|
| Application Notes | recommended for detection of St3Gal-II of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
