| Product Name | NOXO1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 77-376 mapping at the C-terminus of NOXO1 of human origin |
| Modification Notes | NADPH oxidase (NOX) proteins include a membrane-bound flavocytochrome containing two subunits (gp91 phox and p22 phox) and the cytosolic proteins p47 phox and p67 phox. NOX activation leads to the formation of a complex that catalyzes the transfer of electrons from NADPH to molecular oxygen, therefore generating reactive oxygen species (ROS). NOXO1 (NADPH oxidase organizer 1), also designated SH3 and PX domain-containing protein 5 and Nox-organizing protein 1, is a 376 amino acid protein that targets NOX to different subcellular compartments and also targets NOX activators to NOX. Interestingly, NOXO1 is required for the synthesis of otoliths, cystalline structures of the inner ear that are involved in the perception of gravity. There are four isoforms of NOXO1 that are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NOXO1 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 77-376 mapping at the C-terminus of NOXO1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 77-376 mapping at the C-terminus of NOXO1 of human origin |
| Entrez Gene | 124056 |
|---|
| Application Notes | recommended for detection of NOXO1 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
