epitope corresponding to amino acids 506-564 mapping within an internal region of TAO2 of human origin
Modification Notes
Several mammalian kinases have been identified with sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20. Ste20 is involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades, and it lies upstream of a MEK kinase. Thousand and one amino acid protein 2 (TAO2), also designated prostate-derived Ste20-like kinase 1 (PSK1) or kinase from chicken homolog C (KFC-C), belongs to the Ste20 subfamily of the Ser/Thr protein kinase family. TAO2 acts as an activator of the JNK MAP kinase pathway through the specific activation of MKK3 and MKK6 kinases. It is a multi-pass membrane protein detected in cytoplasmic vesicle membranes. TAO2 is ubiquitously expressed with highest levels found in brain and testis.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TAO2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 506-564 mapping within an internal region of TAO2 of human origin
Tissue Specificity
epitope corresponding to amino acids 506-564 mapping within an internal region of TAO2 of human origin
recommended for detection of TAO2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.