epitope corresponding to amino acids 571-652 mapping at the C-terminus of Oatp4 of rat origin
Modification Notes
The organic anion transporter family of proteins mediate hepatic uptake of cardiac glycosides. Oatp4, also known as Slco1b2 (solute carrier organic anion transporter family member 1B2), Slc21a10 (solute carrier family 21 member 10) or LST-1 (liver-specific organic anion transporter 1), is a 689 amino acid member of the organic anion transporter protein family. As a multi-pass membrane protein, Oatp4 mediates the Na+ transport of bromosulfophthalein, taurochlate and other organic anions. Oatp4 is also thought to transport steroid conjugates, such as 17-beta-glucuronosyl estradiol, dehydroepiandrosterone sulfate, estrone-3-sulfate and prostaglandin E2. Oatp4 is liver-specific and expressed as three isoforms produced by alternative splicing.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Oatp4 isoforms 1, 2 and 3 of rat and, to a lesser extent, mouse origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 571-652 mapping at the C-terminus of Oatp4 of rat origin
Tissue Specificity
epitope corresponding to amino acids 571-652 mapping at the C-terminus of Oatp4 of rat origin