| Product Name | ABCB6 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 551-630 mapping within an internal region of ABCB6 of human origin |
| Modification Notes | The ATP-binding cassette (ABC) superfamily is comprised of transmembrane proteins involved in energy-dependent transport of a variety of substrates across membranes. ABCB6 is a 842 amino acid protein belonging to the heavy metal importer subfamily of the ABC transporter family. Up-regulated at the protein level by cellular porphyrins, ABCB6 binds to heme and a porphyrin and assists in their ATP-dependent uptake into the mitochondria. ABCB6 also plays an important role in heme synthesis. ABCB6 contains one ABC transmembrane type-1 domain and one ABC transporter domain and forms a homodimer in the mitochondrion outer membbrane, plasma membrane and the Golgi apparatus. Widely expressed, ABCB6 has highest expression in skeletal muscle and heart. ABCB6 is present as two isoforms produced by alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ABCB6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 551-630 mapping within an internal region of ABCB6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 551-630 mapping within an internal region of ABCB6 of human origin |
| Entrez Gene | 10058 |
|---|
| Application Notes | recommended for detection of ABCB6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
