Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing nuclear localization.| Product Name | ANKRD38 Antibody (L-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD38 (ankyrin repeat domain 38), also known as KANK4 (KN motif and ankyrin repeat domains 4) or kidney ankyrin repeat-containing protein 4, is a 995 amino acid coiled-coil protein that contains five ANK repeats. ANKRD38 is conserved in cow, mouse, rat and chicken, and exists as two alternatively spliced isoforms. Expressed in colon, kidney, liver, lung and skeletal muscle, ANKRD38 may function in the formation of actin stress fibers. ANKRD38 is encoded by a gene that maps to human chromosome 1p31.3. As the largest human chromosome, chromosome 1 makes up approximately 8% of the human genome and contains 260 million base pairs encoding 3,000 genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ANKRD38 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ANKRD family members also reactive with additional species, including canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of ANKRD38 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of ANKRD38 of human origin |
| Entrez Gene | 163782 |
|---|
Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing nuclear localization.| Application Notes | recommended for detection of ANKRD38 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ANKRD family members also reactive with additional species, including canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
