| Product Name | AKR1A1 Antibody (H-115) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 211-325 mapping at the C-terminus of AKR1A1 of human origin |
| Modification Notes | AKR1A1 (aldo-keto reductase family 1 member A1), also known as ALR (aldehyde reductase), DD3 (dihydrodiol dehydrogenase 3) or ALDR1 (alcohol dehydrogenase), is a widely and abundantly expressed member of the aldo-keto reductase (AKR) family of proteins. Members of the AKR family are soluble NADPH-dependent oxidoreductases. They play important roles in the metabolism of drugs, carcinogens and reactive aldehydes. AKR1A1 exists as a monomer and catalyzes the reduction of xenobiotic and biogenic aldehydes and ketones to their corresponding alcohols. In particular, AKR1A1 efficiently catalyzes medium-chain and aromatic aldehydes. AKR1A1 participates in the biosynthetic pathways of cholesterol and triglyceride and plays a role in the activation of polycyclic aromatic hydrocarbons (PAHs). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of AKR1A1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 211-325 mapping at the C-terminus of AKR1A1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 211-325 mapping at the C-terminus of AKR1A1 of human origin |
| Application Notes | recommended for detection of AKR1A1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
