| Product Name | Tβ-15a/b Antibody (FL-45) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-45 representing full length Tβ-15a/b of human origin |
| Modification Notes | ∫-thymosins are a family of small, water-soluble peptides. They are molecules with multiple and diverse intracellular and extracellular functions. ∫-thymosins are known for binding G-Actin and disturbing the assembly of F-Actin. T∫-15a (TMSB15A), also designated neuroblastoma thymosin ∫ (NB T∫), or thymosin-like protein 8, is significantly similar to its family members thmyosin-∫15b (T∫-15b), thmyosin-∫4 (T∫-4) and thymosin-∫10 (T∫-10). T∫-15a is a 44 amino acid protein expressed in neuroblastomas that localizes to the cytoplasm. It interacts with G-Actin and is involved in tissue invasion, cell growth and cell motility. Interference of T∫-15a expression has been shown to decrease cell invasion. T∫-15a may play a role in tumor development and progression. A newly described isoform of thmyosin-∫15, T∫-15b is transcribed from a different gene (TMSB15B) and encodes a protein identical to T∫-15a. The two gene isoforms are subject to different transcriptional regulation and have distinct expression. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Tβ-15a/b and, to a lesser extent, other Tβ family members of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-45 representing full length T&beta -15a/b of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-45 representing full length Tβ-15a/b of human origin |
| Entrez Gene | 11013 |
|---|
| Application Notes | recommended for detection of Tβ-15a/b and, to a lesser extent, other Tβ family members of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
