Application
Western blot analysis of ZDHHC2 expression in HeLa (A), Jurkat (B) and MIA PaCa-2 (C) whole cell lysates.| Product Name | ZDHHC2 Antibody (S-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ZDHHC2 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC2 (zinc finger, DHHC-type containing 2), also known as DHHC2, ZNF372, REAM or REC, is a 367 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger. The ubiquitously expressed ZDHHC2 protein functions as a palmitoyltransferase that uses palmitoyl-CoA and catalyzes the conversion of target proteins, namely GAP-43 and PSD-95, to S-palmitoyl proteins. Defects in the gene encoding ZDHHC2 are found in colorectal cancer and hepatocellular carcinoma, suggesting a role for ZDHHC2 in tumorigenesis. The gene encoding human ZDHHC2 maps to chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZDHHC2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZDHHC family members also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ZDHHC2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ZDHHC2 of human origin |
| Entrez Gene | 51201 |
|---|
Application
Western blot analysis of ZDHHC2 expression in HeLa (A), Jurkat (B) and MIA PaCa-2 (C) whole cell lysates.| Application Notes | recommended for detection of ZDHHC2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other ZDHHC family members also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
