| Product Name | TREK-1 Antibody (H-75) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 352-426 mapping within a C-terminal cytoplasmic domain of TREK-1 of human origin |
| Modification Notes | TREK-1 (also designated TWIK-related K+ channel) and TREK-2 are members of the tandem-pore K+ channel family and belong to the class of mechanosensitive and fatty acid-stimulated K+ channels. TREK-1 has an outwardly rectifying current-voltage relationship, while TREK-2 shows inward rectification. Both TREK-1 and TREK-2 are activated by arachidonic acid and other naturally occurring unsaturated free fatty acids. These family members possess two pore-forming domains and four transmembrane segments. TREK-2 is a 538-amino acid protein and shares 65% amino acid sequence identity with TREK-1. TREK-1 is expressed in many different tissues, particularly lung and brain, while TREK-2 is expressed mainly in the cerebellum, spleen, and testis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TREK-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 352-426 mapping within a C-terminal cytoplasmic domain of TREK-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 352-426 mapping within a C-terminal cytoplasmic domain of TREK-1 of human origin |
| Entrez Gene | 3776 |
|---|
| Application Notes | recommended for detection of TREK-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
