| Product Name | POMT1 Antibody (H-42) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 227-268 mapping within an internal region of POMT1 of human origin |
| Modification Notes | O-mannosylation is an essential protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases. The POMT1 (protein O-mannosyltransferase 1) protein consists of 725 amino acids. POMT1 contains seven to twelve presumed transmembrane regions and a C-terminal ER membrane retention signal; RT-PCR reveals several mRNA splice variants. RNA dot blot analysis indicates ubiquitous expression of POMT1, with maximum levels in testis and high levels in fetal brain and pituitary tissues. Walker-Warburg syndrome (WWS), a severe, recessive, congenital muscular dystrophy associated with defects in neuronal migration that produce complex brain and eye abnormalities, is caused by mutations in the POMT1 gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of POMT1 isoforms 1, 2 and 3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 227-268 mapping within an internal region of POMT1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 227-268 mapping within an internal region of POMT1 of human origin |
| Entrez Gene | 10585 |
|---|
| Application Notes | recommended for detection of POMT1 isoforms 1, 2 and 3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
