The acyl-CoA synthetase medium-chain (ACSM) family is comprised of ACSM1, ACSM2A, ACSM2B, ACSM3, ACSM4 and ACSM5, which encode for enzymes catalyzing the activation of medium-chain length fatty acids. ACSM3 is a 586 amino acid protein has a broad substrate specificity and utilizes magnesium as a cofactor. The gene encoding ACSM3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ACSM3 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-50 mapping at the N-terminus of ACSM3 of mouse origin
Tissue Specificity
epitope corresponding to amino acids 1-50 mapping at the N-terminus of ACSM3 of mouse origin
Application
Application
Western blot analysis of ACSM3 expression in non-transfected: (A) and human ACSM3 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of ACSM3 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.