Application
Western blot analysis of RoXaN expression in non-transfected: (A) and mouse RoXaN transfected: (B) 293T whole cell lysates.| Product Name | RoXaN Antibody (N-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of RoXaN of human origin |
| Modification Notes | RoXaN (zinc finger CCCH-type containing 7B), is a 993 amino acid protein likely involved in translational regulation whose alternative names include rotavirus 'X'-associated non-structural protein, ubiquitous tetratricopeptide containing protein RoXaN, ZC3H7B, FLJ13787, KIAA1031, or DKFZp434K0920. RoXaN localizes to the nucleus and has been identified as a novel cellular protein-binding partner for the rotavirus nonstructural protein NSP3, which is involved in rotavirus replication. RoXaN’s nuclear localization is known to appear disguised upon infection with rotavirus A. Two RoXaN isoforms exist as a result of alternative splicing, and RoXaN also contains one C2H2-type zinc finger, three TPR repeats and four C3H1-type zinc fingers. RoXaN contains one paxillin leucine-aspartate repeat (LD) motif in addition to a coiled-coil region which assist in protein-protein interactions. The gene encoding RoXaN maps to human chromosome 22q13.1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RoXaN of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of RoXaN of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of RoXaN of human origin |
| Entrez Gene | 23264 |
|---|
Application
Western blot analysis of RoXaN expression in non-transfected: (A) and mouse RoXaN transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of RoXaN of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
