| Product Name | SPAG4 Antibody (H-55) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 212-266 mapping within an internal region of SPAG4 of human origin |
| Modification Notes | Mammalian sperm flagellum contain two cytoskeletal structures associated with the the axoneme: the outer dense fibers and the fibrous sheath. The outer dense fibers surround the axoneme in the midpiece and principal piece, whereas the fibrous sheath surrounds outer dense fibers of the tail of the principal piece. SPAG4 (sperm associated antigen 4), also known as outer dense fiber-associated protein SPAG4, is a 427 amino acid multi-pass membrane protein that may play a role in the organization and assembly of outer dense fibers (ODFs). Existing as a homodimer, SPAG4 interacts with Odf1 and is suggested to associate with microtubules. SPAG4 localizes to the transient manchette and axoneme of elongating spermatids and epididymal sperm. Containing one SUN domain, SPAG4 is considered a potential cancer marker. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SPAG4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 212-266 mapping within an internal region of SPAG4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 212-266 mapping within an internal region of SPAG4 of human origin |
| Entrez Gene | 6676 |
|---|
| Application Notes | recommended for detection of SPAG4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
