epitope mapping within an internal region of UBAC2 of human origin
Modification Notes
UBAC2 (ubiquitin-associated domain-containing protein 2), also known as PHGDHL1 (phosphoglycerate dehydrogenase-like protein 1), is a 344 amino acid multi-pass membrane protein that contains one UBA domain and is expressed as multiple alternatively spliced isoforms. The gene encoding UBAC2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of UBAC2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with isoform 5 also reactive with additional species, including equine, canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of UBAC2 of human origin
Tissue Specificity
epitope mapping within an internal region of UBAC2 of human origin
Western blot analysis of UBAC2 expression in mouse brain tissue extract.
Application Notes
recommended for detection of UBAC2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with isoform 5 also reactive with additional species, including equine, canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.