| Product Name | DDX21 Antibody (H-94) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 684-777 mapping near the C-terminus of DDX21 of human origin |
| Modification Notes | DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX21 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 21), also known as GUA or GURDB, is a 783 amino acid protein that localizes to the nucleus and contains one helicase C-terminal domain and one helicase ATP-binding domain. Existing as multiple alternatively spliced isoforms, DDX21 functions as a component of the multi-protein B-WICH complex and acts as both a helicase that can unwind double-stranded RNA and as a foldase that can introduce secondary structures into single-stranded RNA. DDX21 exists as an autoantigen in people affected by watermelon stomach disease which is often characterized by chronic gastrointestinal bleeding. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DDX21 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 684-777 mapping near the C-terminus of DDX21 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 684-777 mapping near the C-terminus of DDX21 of human origin |
| Entrez Gene | 9188 |
|---|
| Application Notes | recommended for detection of DDX21 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
