epitope corresponding to amino acids 330-523 mapping within an internal region of TTC30A of human origin
Modification Notes
The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins and acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TTC30A (tetratricopeptide repeat domain 30A) and TTC30B (tetratricopeptide repeat domain 30B) are cell projection proteins that belong to the TTC30/dfy-1/fleer family. TTC30A and TTC30B contain eight TPR repeats and may be required for polyglutamylation of axonemal tubulin. Both TTC30A and TTC30B may be involved in anterograde intraflagellar transport (IFT), which is a process where cilia precursors are transported from the base of the cilium to the site of incorporation at the tip. TTC30A and TTC30B consists of 665 amino acids and are encoded by a gene located on human chromosome 2q31.2.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TTC30A and TTC30B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 330-523 mapping within an internal region of TTC30A of human origin
Tissue Specificity
epitope corresponding to amino acids 330-523 mapping within an internal region of TTC30A of human origin
recommended for detection of TTC30A and TTC30B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.