| Product Name | Cdc2L5 Antibody (J-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of CDC2L5 of mouse and human origin by WB, IF, IHC(P) and ELISA |
| Modification Notes | The eukaryotic cell division cycle consists of a number of gene-controlled sequences that involve cyclin-dependent kinases (Cdks) and cell division control (Cdc) proteins. Cdc2L5 (cell division cycle 2-like 5), also known as CHED or CDC2L, is a member of the cyclin-dependent serine/threonine protein kinase family that plays a role in cell differentiation and apoptosis. Expressed in liver, brain and muscle, Cdc2L5 is thought to control key events in the mitotic cycle and may be involved in the development of blood cells. Due to its role in mitosis, overexpression of Cdc2L5 is implicated in the development of neuroblastoma and glioblastoma tumors, suggesting a possible role for Cdc2L5 in carcinogenesis. Cdc2L5 contains one protein kinase domain and is expressed as two different isoforms produced by alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFIHCELISA |
| WB:1:500~1:2000 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of CDC2L5 of mouse and human origin by WB IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of CDC2L5 of mouse and human origin by WB, IF, IHC(P) and ELISA |
| Entrez Gene | 8621 |
|---|
| Application Notes | WB:1:500~1:2000 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
